Here's a brief bit from the BeBoBio Google Groups page:
groups.google.com/group/bebobio

Last year (May 2007) I came across an interesting article in
Scientific American by Peter Duesberg arguing against the "mutation"
theory of cancer in favor of the "chromosomal" theory. Here's a link
to a current article on the same subject:
www.berkeley.edu/news/medi...istance...

The reason I'm posting this here, even though it's not directly
related to biomodeling, is that this seems to be an area in which
biomodeling or bio-informatics could be fruitful. Minimally, it seems
like a data mining approach to RNA profiles from individual cells from
the same tumor would yield some interesting information.

Something I'd be curious about in light of these two theories - Why are there spontaneous rejections
of tumors? I've seen these rejections in mouse models of cancer.
Another area of cancer research that isn't directly related to
biomodeling, but still interests me is the idea of "cancer stem
cells", the idea that only a small fraction of the cells in a tumor are capable
of regenerating the tumor. I came across an interesting link when I
was looking at a sequence analysis and data mining program called
"Gemini".

One of the researchers involved with Gemini is associated with the
Oncology Research Institute, which has a link to a short page talking
about their 5 broad based cancer platforms, well worth a quick
glance: www.ori.nus.edu.sg/research.html It includes
information about cancer stem cells and epigenetics.

Later, R.